| Date | Time | Opponent | Rank | Site | Result | Attendance | Source |
|---|
| September 1 | 6:00 p.m. | UNC Pembroke* | No. 9 | W 28–23 | 4,337 | [1] |
| September 8 | 1:00 p.m. | at Concord* | No.
8 | W 30–22 | 1,112 | [2] |
| September 15 | 12:00 p.m. | vs.Alabama A&M fires longtime HBCU coach Connell MaynorMorehouse* | No. 5 | W 55–21 | 10,000 | [3] |
| September 22 | 6:00 p.m. | Virginia Union | No. 5 | - Bowman Gray Stadium
- Winston-Salem, NC
| W 35–6 | 6,133 | [4] |
| September 29 | 1:00 p.m. | at Bowie State | No.
5 | W 35–3 | 2,964 | [5] |
| October 6 | 4:00 p.m. | at Johnson C. Smith | No.Alabama A&M University Parts Ways with Head Coach Connell Maynor4 | W 63–7 | 6,147 | [6] |
| October 13 | 1:30 p.m. | St. Augustine's | No. 3 | - Bowman Gray Stadium
- Winston-Salem, NC
| W 56–37 | 9,321 | [7] |
| October 20 | 1:30 p.m. | Livingstone | No.
2 | - Bowman Gray Stadium
- Winston-Salem, NC
| W 58–0 | 17,123 | [8] |
| October 27 | 1:00 p.m. | at Shaw | No. 2 | W 62–31 | 2,561 | [9] |
| November 3 | 1:30 p.m. | at Fayettevil Alabama A&M releases head football coach Connell Maynor ZACA
|